Cross Pharma Synergeia Flavonoids - Dietary Supplement For Swollen & Tired Feet, 20 effervescent tablets

It contributes to the normal formation of collagen for the functioning of blood vessels and the protection of cells from oxidative stress. The preparation is a combination of diosmin, hesperidin, troxerutin and vitamin C. Diosmin is a semi-synthetic phlebotropic drug (modified hesperidin), a member of the flavonoid family. Diosmin prolongs the vasoconstrictor effect of norepinephrine on the venous wall, resulting in an increase in venous tone and consequently a decrease in venous capacity, distensibility and stasis. Diosmin improves lymphatic drainage by increasing the frequency and intensity of contractions of the lymphatic system, increasing the total number of functional capillaries of the lymphatic system. Finally, diosmin reduces the expression of adhesion molecules on the endothelium (ICAM1, VCAM1), and inhibits the adhesion, migration and activation of leukocytes at the capillary level. This leads to a reduction in the release of inflammatory mediators, mainly oxygen free radicals and prostaglandins (PGE2, PGF2a). Oxerutins are flavonoids synthesized from rutin. They act on the smallest blood vessels (capillaries) by reducing microleakage of water and other substances through the walls. They reduce edema caused by diseases of the veins of the legs and relieve the usual associated symptoms, such as pain, fatigue, heavy legs and cramps. Ascorbic acid is an essential component of the human body. Ascorbic acid has a strong reducing effect. The metabolic role of ascorbic acid is multidimensional. In the intestine, it promotes the absorption of non-heme iron. It participates in the synthesis of hydroxyproline, corticosteroids and carnitine. It is a precursor of oxalates that are excreted by the kidneys. It is a powerful antioxidant factor in the metabolism of lipids, cell membranes and vitamins.

Shipping with ACS Courier

For orders that do not exceed 3kg of volumetric weight*, the shipping cost is €3.00 when the order is under €50. For orders over this amount, shipping is free!
For orders over 3kg of volumetric weight*, there is an additional charge of €2.30 per extra kilogram.
If the chosen payment method is cash on delivery, there is an additional fee of €2.50.

BOX NOW Shipments up to €150

Shipping costs are calculated as follows:

• €5.80 for a medium locker (dimensions 17x45x62cm, up to 4kg)

• €6.90 for a large locker (dimensions 35x45x62cm, up to 7kg)

For orders over €150, shipping is free.

The parcel remains in the locker for 48 hours, with the possibility to extend for an additional 24 hours upon user request.

Shipping to Cyprus and International Destinations

Orders are shipped via DHL Courier. Shipping costs are calculated based on the destination zone and product weight. You will be notified via email of the final shipping cost.
Prepayment via bank transfer or card is required for order shipment.

In-store Pickup

Orders marked as “Pickup from store” are available after confirmation, provided all products are in stock. You will receive an SMS notification when your order is ready.
Pickup is available at our physical store in Mastampas, Heraklion:

Smpokou 8 & Leftheraiou, Saridakis Pharmacy

Opening hours:
Monday - Friday: 08:00–21:00
Saturday: 08:00–20:00

The order must exceed €15 in value.

Orders remain available at the pharmacy for up to 5 business days, after which they are automatically canceled.

If any of the ordered products are not immediately available in our store, the waiting time may be up to 5 business days. You will be notified via email about product availability.

*Volumetric Weight (in kg) = (length × width × height in cm) / 5,000