Avene Cleanance Comedomed Cream - Cream For Acne-Prone Skin, 30ml

Cleanance Comedomed, an innovation from Avène Thermal Spring Water Laboratories, has proven clinical efficacy from day 7*, tackling blemishes at their source and limiting their reappearance. Specialised care for oily, acne-prone skin, Cleanance Comedomed is formulated with Comedoclastin™, a plant extract from the seeds of the Milk Thistle plant. This active ingredient with patented properties** directly targets blackheads, reduces existing blackheads and whiteheads, limits the appearance of new ones and regulates excessive sebum production. Cleanance Comedomed is suitable for adults and adolescents from the age of 12, applied twice a day, morning and evening, and offers clinically proven*** action against the reappearance of blemishes. Non-comedogenic formula, highly tolerated* for acne-prone skin, fast absorption, non-greasy texture that gives the skin a matte effect. *Tolerance and efficacy study under dermatological control on 51 subjects, using Cleanance Comedomed twice a day for 56 days. ** Patented. ***International clinical follow-up study, 90% of patients without acne recurrence at 6 months, (as defined by recurrence in the GEA protocol ≥3 requiring the introduction of medication - oral or topical), 48 subjects, two applications per day of Cleanance Comedomed for six months.

The effectiveness of the product is proven within 7 days* • reduces blemishes within 7 days¹ • limits their reappearance by 90%² • reduced blemishes by 45% over 2 months³, a significant result compared to the control group ¹Tolerance and efficacy study under dermatological control in 51 subjects, using Cleanance Comedomed twice a day for 56 days. ²International clinical follow-up study, 90% of patients without acne recurrence at 6 months, (as defined by recurrence in the GEA protocol≥3 requiring the introduction of oral or topical medication), 48 subjects, 2 applications per day of Cleanance Comedomed only for 6 months. ³36 subjects with mild to moderate blemishes. Comparative clinical study (application twice/day, subjects=18), control group (subjects=18) for 56 days.

How to use

2 times a day. Usage tips: Apply 1 dose of Cleanance Comedomed to your fingertips, on a clean face.

• Start by dabbing it on your T-zone and cheeks.
• Make circular movements for better absorption of the product.
• Finish by applying to the cheeks and lower face. Repeat the application morning and evening.

Advice from the experts:

We only have one piece of advice, adopt a short but essential skincare routine!

• 1 careful facial cleansing or makeup removal: morning and evening!!!
• 1 treatment against imperfections: also morning and evening.

Shipping with ACS Courier

For orders that do not exceed 3kg of volumetric weight*, the shipping cost is €3.00 when the order is under €50. For orders over this amount, shipping is free!
For orders over 3kg of volumetric weight*, there is an additional charge of €2.30 per extra kilogram.
If the chosen payment method is cash on delivery, there is an additional fee of €2.50.

BOX NOW Shipments up to €150

Shipping costs are calculated as follows:

• €5.80 for a medium locker (dimensions 17x45x62cm, up to 4kg)

• €6.90 for a large locker (dimensions 35x45x62cm, up to 7kg)

For orders over €150, shipping is free.

The parcel remains in the locker for 48 hours, with the possibility to extend for an additional 24 hours upon user request.

Shipping to Cyprus and International Destinations

Orders are shipped via DHL Courier. Shipping costs are calculated based on the destination zone and product weight. You will be notified via email of the final shipping cost.
Prepayment via bank transfer or card is required for order shipment.

In-store Pickup

Orders marked as “Pickup from store” are available after confirmation, provided all products are in stock. You will receive an SMS notification when your order is ready.
Pickup is available at our physical store in Mastampas, Heraklion:

Smpokou 8 & Leftheraiou, Saridakis Pharmacy

Opening hours:
Monday - Friday: 08:00–21:00
Saturday: 08:00–20:00

The order must exceed €15 in value.

Orders remain available at the pharmacy for up to 5 business days, after which they are automatically canceled.

If any of the ordered products are not immediately available in our store, the waiting time may be up to 5 business days. You will be notified via email about product availability.

*Volumetric Weight (in kg) = (length × width × height in cm) / 5,000